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| Introduction |
| Early & mid-term results for EVAR Trial 1 |
| Mid-term results for EVAR Trial 2 |
| Current interpretation for EVAR Trial 1 |
| Current interpretation for EVAR Trial 2 |
| Non-expert summary |
| Participating Centres |
| Ethical Approval |
| Outcome Measures |
| Power Calculations |
| Patients |
| Sample group |
| Randomisation |
| Subvention fund |
| Recruitment |
| Follow-up |
| Trial management and data monitoring |
The recruitment target was exceeded in this trial due to the enormous enthusiasm of our trial centres and these are listed below with the nominated surgeon, radiologist and coordinator for each hospital. We also thank all the other clinicians within the named hospitals and from local supporting hospitals, who were responsible for the referral of almost one third of the patients to the trial centres.
EVAR Trial participants
Applicants
Professor RM Greenhalgh (lead applicant), Professor DJ Allison, Professor
PRF Bell, Professor MJ Buxton, Mr PL Harris, Professor BR Hopkinson, Professor
JT Powell, Professor IT Russell, Professor SG Thompson.
Trial Management Committee
Professor RM Greenhalgh (Chair), Miss LC Brown (Trial Manager), Mr JD Beard,
Professor MJ Buxton, Mr PL Harris, Professor JT Powell, Dr JDG Rose, Professor
IT Russell, Professor MJ Sculpher, Professor SG Thompson.
Trial Steering Committee
Professor RJ Lilford (Chair), Professor Sir PRF Bell, Professor RM Greenhalgh,
Dr SC Whitaker.
Data Monitoring & Ethical Committee
Professor PA Poole-Wilson (Chair), Professor WB Campbell, Dr EC Coles, Dr
MRE Dean, Professor CV Ruckley, Dr MST Ruttley.
Endpoints Committee
Professor JT Powell (Chair), Dr JS Gibbs, Miss A Halliday.
Data management and statistical analyses
Miss LC Brown (Trial Manager), Mr G Barton, Mr D Epstein, Dr GPS Kwong, Ms
S Macran, Mr A Manca, Dr J Reise, Mrs A Williams.
Regional Trial Participants Committee
Represented by one surgeon, radiologist and coordinator per centre. (Number
in brackets indicates number of patients entered into EVAR trial 1, EVAR Trial
2)
Mr K Varty, Dr C Cousins, Addenbrookes Hospital, Cambridge (2, 0)
Mr RJ Hannon, Dr L Johnston, Belfast City Hospital (34, 16)
Professor AW Bradbury, Dr MJ Henderson, Birmingham Heartlands Hospital (3,
1)
Mr RA Salaman, Dr D Gavan, Blackburn Royal Infirmary (0, 0)
Mr SD Parvin, Dr DFC Shepherd, Bournemouth General Hospital (44, 13)
Professor RM Greenhalgh, Dr AW Mitchell, Charing Cross Hospital, London (22,
1)
Professor PR Edwards, Dr GT Abbott, Countess of Chester Hospital (11, 3)
Mr DJ Higman, Dr A Vohra, Coventry & Walsgrave Hospital (7, 0)
Mr S Ashley, Dr C Robottom, Derriford Hospital, Plymouth (1, 0)
Mr MG Wyatt, Dr JDG Rose, Freeman Hospital, Newcastle (104, 4)
Mr D Byrne, Dr R Edwards, Gartnavel General Hospital, Glasgow (4, 3)
Mr DP Leiberman, Dr DH McCarter, Glasgow Royal Infirmary (13, 2)
Mr PR Taylor, Dr JF Reidy, Guy’s & St. Thomas’ Hospital, London
(49, 46)
Mr AR Wilkinson, Dr DF Ettles, Hull Royal Infirmary (18, 7)
Mr AE Clason, Dr GLS Leen, James Cook University Hospital, Middlesborough
(18, 1)
Mr NV Wilson, Dr M Downes, Kent & Canterbury Hospital (0, 0)
Mr SR Walker, Dr JM Lavelle, Lancaster General Infirmary (4, 4)
Mr MJ Gough, Dr S McPherson, Leeds General Infirmary (24, 10)
Mr DJA Scott, Dr DO Kessell, Leeds St. James’s Hospital (10, 1)
Professor Sir PRF Bell, Mr R Sayers, Dr NG Fishwick, Leicester Royal Infirmary
(99, 32)
Mr PL Harris, Dr DA Gould, Liverpool Royal Hospital (96, 26)
Professor MG Walker, Dr NC Chalmers, Manchester Royal Infirmary (55, 29)
Mr A Garnham, Dr MA Collins, New Cross Hospital, Wolverhampton (0, 1)
Mr E Griffiths, Dr S Chakraverty, Ninewells Hospital, Dundee (0, 0)
Mr JD Beard, Dr PA Gaines, Northern General Hospital, Sheffield (57, 20)
Mr MY Ashour, Dr R Uberoi, Queen Elizabeth Hospital, Gateshead (11, 2)
Mr B Braithwaite, Dr SC Whitaker, Queen’s Medical Centre, Nottingham
(72, 23)
Mr JN Davies, Dr S Travis, Royal Cornwall Hospital, Truro (15, 6)
Mr G Hamilton, Dr A Platts, Royal Free Hospital, London (20, 14)
Mr A Shandall, Dr BA Sullivan, Royal Gwent Hospital (1, 0)
Mr M Sobeh, Dr M Matson, Royal London Hospital (0, 1)
Mr AD Fox, Dr R Orme, Royal Shrewsbury Hospital (6, 0)
Mr W Yusef, Dr T Doyle, Royal Sussex County Hospital, Brighton (0, 0)
Professor M Horrocks, Dr J Hardman, Royal United Hospital, Bath (26, 3)
Mr PHB Blair, Dr PK Ellis, Royal Victoria Hospital, Belfast (26, 13)
Mr Gareth Morris, Dr A Odurny, Southampton General Hospital (27, 5)
Mr R Vohra, Dr M Duddy, Selly Oak Hospital, Birmingham (16, 6)
Professor M Thompson, Mr TML Loosemore, Dr AM Belli, Dr R Morgan, St.George’s
Hospital, London (33, 17)
Mr M Adiseshiah, Dr JAS Brookes, University College Hospital, London (40,
23)
Mr RJ Whiston, Dr A Wood, University Hospital of Cardiff (0, 0)
Professor CN McCollum, Dr R Ashleigh, University Hospital of South Manchester
(114, 5)
Trial Co-ordinators
Marion Aukett, Sara Baker, Emily Barbe, Jocelyn Bell, Jo Blundell, Dee Boardley,
Sheila Boyes, Oliver Brown, Jennie Bryce, Tina Chance, Joanne Coleman, Chryz
Cosgrove, Trez Dennison, Carol Devine, Nikki Dewhirst, Alison Kite, Barry
Errington, Cathy Fisher, Paul Fulford, Moira Gough, Norma Gourlay, Sue Hamilton,
Rona Hooper, Jill Horne, Liz Horrocks, Bet Hughes, Tracey Hutchings, Marilyn
Ireland, Claire Judge, Linda Kelly, Julie Kemp, Milla Kivela, Chris Lee, Lorraine
Linekar, Jeanette Lock, Asif Mahmood, Linda March, Janis Martin, Nick Matharu,
Kathy McGuigen, Phyl Morris-Vincent, Shirley Murray, Allison Murtagh, Gareth
Owen, Jane Rowley, Julie Sinclair, Nicky Sinclair, Sarah Spencer, Victoria
Taylor, Cindy Tomlinson, Sue Ward, Vera Wealleans, Julia West, Karen White,
Jenny Williams, Lesley Wilson.